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Biphasic Mesothelioma is one of the three cell types of Mesothelioma cancer. It is also referred to as "mixed" because it has characteristics of Epithelioid and Sarcomatoid cell types. Biphasic Mesothelioma represents 25%-30% of pleural mesothelioma cases. The only cause is exposure to Asbestos, and the diagnosis is confirmed by tissue or fluid biopsy.

Biphasic Mesothelioma Symptoms

General symptoms most patients experience before diagnosis are shortness of breath, cough, and chest pain. The problem is that these symptoms generally apply to many conditions, so they are not good indicators by themselves.

As the disease progresses, additional symptoms may also include:

  • Persistent cough
  • Shortness of breath
  • Abdominal or chest pain
  • Decreased appetite and weight loss
  • Fatigue
  • Fluid build-up in lungs or abdomen
  • Nausea and vomiting
  • Anemia
  • Coughing up blood

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Diagnosing Biphasic Mesothelioma

Biphasic Mesothelioma is often very difficult to diagnose because Biphasic tumors can closely resemble tumors caused by other conditions.

As the name suggests, Biphasic tumors are a mixed form of Epithelioid and Sarcomatoid cell types. To be classified as Biphasic, each of these cell types must account for at least 10% of the tumor.

Typically a tissue biopsy is required to make an official diagnosis of Biphasic Mesothelioma.

The analysis of needle-core will show both epithelioid and sarcomatoid cell types. A fluid biopsy is also possible, but it can be difficult to capture both types of cells in the fluid.

Biphasic Mesothelioma Treatment

The treatment options for Epithelioid Mesothelioma mainly consists of chemotherapy, radiation, and immunotherapy.

Combination therapies and surgical intervention are called a multimodal approach: the choice of treatment or combination of medicines depends on the tumor location and stage.

Biphasic and Epithelioid tumors are better candidates for surgical interventions.

Combination (multimodal) treatments generally have better results because the cancer is made up of different cell types that respond differently to each treatment type.

More aggressive treatment plans are often better suited for Biphasic Mesothelioma patients with a higher percentage of epithelioid cells.

Biphasic Mesothelioma Prognosis

Patients diagnosed with Biphasic Mesothelioma can have a wide range of outcomes.

Because this type of Mesothelioma is a combination of the other two main types, the doctors first have to determine the ratio of epithelioid and sarcomatoid cells in the tumor to develop the most effective treatments.

Patients with the Biphasic type who undergo the multimodal approach of combining surgery, chemotherapy, and immunotherapy can extend their lives by several years.

The long-term prognosis is unique to each person, and it is vital that you work with a cancer center with experience working with Mesothelioma patients.

If you don't have someone in your area, please give us a call, and we can connect you with medical experts on Biphasic Mesothelioma in your area.

Mesothelioma Compensation

If you been diagnosed with Mesothelioma, or if a family member has died from Mesothelioma, Flint Law Firm will be able to help you obtain compensation.

The process of maximizing this Asbestos compensation for you and your family can begin in just a few months.

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Biphasic Mesothelioma FAQ's

What Is The Difference Between Biphasic Versus Other Types Of Mesothelioma?

Biphasic is a combination of both Sarcomatoid and Epithelioid cell types. Biphasic tumors have both elongated cells and larger nuclei and nucleoli. It is different only because of the cell type where the cancer begins. It's only known cause is Asbestos.

Does Asbestos Cause Biphasic Mesothelioma?

Yes. Biphasic Mesothelioma is caused by Asbestos exposure. The fibers enter the human body by breathing or swallowing. Asbestos may then damage the DNA of the surrounding tissue and cause cell death or cancer. There is no other known medical cause of Biphasic Mesothelioma.

Does Biphasic Mesothelioma Qualify For Financial Compensation?

Yes, the Biphasic Mesothelioma qualifies for significant financial compensation. Flint Law Firm will help you recover payments for yourself or a deceased family member. There is a claims process that may not require going to court at all.

Adrianne Andrus

Reviewed by:  Adrienne Andrus
Chief Editor of Flint law Firm LLC
Client Advocate & Product Liability Paralegal since 2015.
Bachelor of Arts Degree in Communication, SIU Edwardsville

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