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Epithelioid Mesothelioma is the most common disease cell type caused by Asbestos exposure. This type of cancer comes from epithelial cell mutations because of asbestos exposure. About 70 percent of mesothelioma cases are of the epithelial cell type. It has a much better prognosis than other cell types because epithelial tumors don't spread as quickly as other types.

Epithelioid Mesothelioma Symptoms

General symptoms most patients experience before diagnosis are shortness of breath, cough, and chest pain. The problem is that these symptoms generally apply to many conditions, so they are not good indicators by themselves. As the disease progresses, additional symptoms may also include:

  • Persistent cough
  • Shortness of breath
  • Abdominal or chest pain
  • Decreased appetite and weight loss
  • Fatigue
  • Fluid build-up in lungs or abdomen
  • Nausea and vomiting
  • Anemia
  • Coughing up blood

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Diagnosing Epithelioid Mesothelioma

A surgical biopsy is needed to determine which cell type is present in the body because epithelioid cells cannot be identified using diagnostic imaging scans.

Doctors perform medical thoracoscopies (a medical procedure of internal examination, biopsy, removal of disease or masses) or similar biopsy procedures.

A tissue sample from the tumor is then extracted for doctors to examine under a high-powered microscope, allowing them to analyze the cancerous cells.

Epithelioid Mesothelioma shares similarities with other cancers and can often be confused with adenocarcinoma, a common form of lung, colon, and breast cancer. That why a biopsy is essential for treatment.

Immunohistochemistry

Immunohistochemistry is a process used to detect proteins called antibodies on the surface of cells. These proteins are analyzed examined to classify a tumor's cell type.‍Pathologists use immunohistochemistry to identify epithelioid mesothelioma cancer and differentiate it from adenocarcinoma and other cancers.

Help your doctor discover the cause of your Mesothelioma symptoms as soon as possible. Keep your regular check-up appointment and share any history of asbestos exposure you have experienced during your life in any mesothelioma consult.

Epithelioid Mesothelioma Treatments

Aggressive treatment plans are considered for patients with this type of Mesothelioma because it responds much better to treatment than other types. If the cancer is found before spreading in the chest cavity, patients are eligible for multimodal therapy.

Multimodal therapy aims to destroy cancer cells using a combination of surgery, radiation, chemotherapy, and immunotherapy.

Multimodal therapy includes a combination of surgery, radiation therapy, and chemotherapy, as They are the most effective therapies for treating mesothelioma.

Not all patients qualify for aggressive treatment plans. For some, the disease is discovered at a stage too advanced to be eligible for surgery. Chemotherapy can still be employed when a surgical resection is no longer an option. The possibility of clinical trials should also be taken into consideration.

Epithelioid Mesothelioma Prognosis

Many factors contribute to life expectancy, and each patient is unique. Through early treatment, some patients can outlive their prognosis significantly. A patient's overall health and age are also significant factors in the projection. On average, patients diagnosed with Epithelioid Mesothelioma have an average life expectancy of six months to more than two years. Clinical trials and various treatments are available for mesothelioma victims, and palliative care can manage symptoms and increase patients' quality of life.

If you need help locating a mesothelioma specialist in your area, please give us a call, Toll-Free at: (855) 883-6447 .

Epithelioid Cell Characteristics

Tumors are classified and differentiated by the type and appearance of the cells of which they are comprised. Normal epithelial cells form the epithelium, one of the four major tissue types in the human anatomy. Those types include epithelial, muscular, connective, and nervous tissue. Epithelial tissues line many of our body cavities and most of our organs.

The structure of epithelial tissue is different depending on its location and function. Epithelial cells can be thin and flat or shaped like columns, cubes, or hexagons.

Cancerous epithelial cells will have a few structural differences, which can be observed using medical machinery. Some of the visual patterns of epithelial cells include epithelioid, biphasic, and sarcomatoid.

These affected cells usually lose uniformity and become atypical in appearance, distinguishing them from healthy cells.

One of the reasons why epithelioid Mesothelioma is less deadly than sarcomatoid Mesothelioma is that epithelioid cells tend to adhere closer together and lack mobility, making them harder to spread throughout the human body.

On the other hand, Sarcomatoid cells are more loosely organized, which allows them to migrate more quickly, leading to a faster onset of metastasis.

Epithelioid Cell Subtypes

Epithelioid Mesothelioma has a few different subtypes, each differentiated from others with unique characteristics. Some of these subtypes are more likely to develop in specific body parts than others. The treatment is not affected by the epithelioid cell subtype. Still, it can help doctors tell Mesothelioma apart from cancers that have similar characteristics.

Here are a few technical descriptions of the more common cell types that have been observed in cases of epithelioid mesothelioma:

Tubulopapillary

The tubulopapillary cell pattern is a prevalent subtype of epithelioid Mesothelioma. Tubulopapillary mesotheliomas often contain well-differentiated cells. This subtype can be mistaken for adenocarcinoma that has spread to the pleura.

Solid

The solid subtype consists of two patterns: Well-differentiated and poorly differentiated. Solid well-differentiated cell patterns are very commonly observed in mesothelioma cancer. They can be mistaken for benign reactive mesothelial hyperplasia.

Solid poorly differentiated cell patterns consist of unorganized cells and have similar appearances to large cell carcinoma and lymphoma.

Adenomatoid

Adenomatoid Mesothelioma is also known as the microglandular mesothelioma subtype. It is a rare occurrence, present in only 6 percent of all pleural mesothelioma cases.

It is challenging for doctors to tell apart this subtype from other tumors such as metastatic pleural adenocarcinoma and benign adenomatoid tumors.

Glandular

Glandular pattern tumors are composed of gland-like structures or acinar structures (cluster of cells resembling a many-lobed "berry" such as a raspberry). This subtype usually develops in the lining of the pleura and can be mistaken for pleural adenocarcinoma.

Epithelioid Mesothelioma FAQs

What Is The Difference Between Epithelioid Versus Other Types Of Mesothelioma?

There are three basic types of Mesothelioma based on the cell type of tumor: Sarcomatoid, Epitheliod, and Biphasic. The Epithelioid Mesothelioma cell type is the most common and is characterized by having larger nuclei and more responsive treatment.

Does Asbestos Cause Epithelioid Mesothelioma?

Yes. Like all mesotheliomas, Epitheliod, Sarcomatoid, and Biphasic can only be caused by Asbestos exposure. The Asbestos fibers are ingested or inhaled and cause genetic damage to mesothelial tissue, which causes it to make continuous copies of the damaged cells.

Does Epithelioid Mesothelioma Qualify For Financial Compensation?

Yes, the Flint law firm can file claims for Epithelioid Mesothelioma, negotiate settlements, and even file a lawsuit to recover financial compensation for our clients. If you have been diagnosed with Epithelioid Mesothelioma, please call us for assistance.

Adrianne Andrus

Reviewed by:  Adrienne Andrus
Chief Editor of Flint law Firm LLC
Client Advocate & Product Liability Paralegal since 2015.
Bachelor of Arts Degree in Communication, SIU Edwardsville

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